Dr. Amar was hardly the only medical professional to witness the possibilities of regenerative cells in the late 1990s. Indeed, scientists had been exploring the boundaries of such cells for decades in laboratory experiments, but always using non-human subjects. It was not until shortly before 2000 that technology allowed researchers to turn their attention towards how they might react in humans. However, few understood exactly why or how the process occurred.

For Dr. Amar, the moment of clarity came in 2001 when he came across an academic journal article written by Patricia Zuk, a professor in the Life Sciences Department at Santa Monica College in California (Human Adipose Tissue Is a Source of Multipotent Stem Cells, the Adult stem cells by opposition to the Embryonic stem cells). Fig 13

Dr Roger Amar in 1997
The article detailed the process of transforming fat cells into bone and into muscle as transplanted stem cells took on the characteristics of a local environment and essentially became one with their host. Nearly four years after the blepharoplasty patient had walked into his office, he realized what had occurred. The transplanted cells had been naturally reprogrammed to reflect their new environment, allowing the regenerative tissue to close the gap left by the patient’s previous surgery.

More than offering a clear picture of what had occurred, the article spurred Dr. Amar to devote his time and energy fully to researching how these cells extracted from fat deposits could be used in his own practice. Balancing the responsibilities of his clinic with his own research, Dr. Amar set out to prove that there were far more beneficial uses to regenerative cells than what he had witnessed all those years before.

Still, the question of how to test his theories remained, leaving the FAMI calculation incomplete. While there was no shortage of evidence that transplanted cells would benefit from being injected directly into muscle tissue, the experimental application of such an approach was nearly impossible given the medical technology that existed at the time.
Fortunately, medical technology was about to take a step forward.

Or visit:   The Amar Clinic website: Stem cells FAMI rejuvenation