In the years since technology and imagination came together to formulate the basis of FAMI, Dr. Amar has worked tirelessly to bring the unique technique out of the laboratory and into the real world. After decades working as a plastic surgeon in the field of cosmetic medicine, Dr. Amar faced a decidedly up-hill battle to not only perfect the technique, but act as an advocate for its benefits when placed next to the array of other options – options he felt to be ultimately inferior to FAMI.

This was no small task, but perhaps more importantly; it was not one he ever believed he would have to face himself. Indeed, when Dr. Amar began piecing together the scientific and technological foundation to create FAMI, he initially thought it would be an innovation that he would pass on to others (fellow scholars and his son) to take forward.

He thought he might plant the seed of FAMI and leave it to the next generation – one he thought might have more energy and motivation – to carry it through to fruition. Fig 33:

This compulsion to follow through was only compounded by an incident in the autumn of 1997, when Dr. Amar witnessed the absolute failure of three cases of fat injection using the most commonly accepted technique of purification and delivery. Frustrated that the existing technology left much to be desired and the belief that it was possible to do better. He repeated the procedure on the same patients using his own graft technique, injecting the cells directly into the muscle at the point of origin using his custom-

designed cannulae. As the grafts took with ease and the results become clear, Dr. Amar knew what he had to do – he had to continue.

For the first time in years, Dr. Amar felt the confidence and energy to invent, with FAMI allowing him to carry his ideas through. As the creator of what he believed to be the next logical, not to mention natural, step in cellular regeneration, Dr. Amar felt compelled to guide the technique forward himself. While other surgeons and researchers might adapt FAMI and the associated tools and technology into their own work, Dr. Amar felt that only he could recognize the true benefit of carrying the technique through to full maturity; a point of development that occurred in mid-summer 2007. Further, it would be his responsibility that those adopting the technique embraced it completely, rather than embracing certain aspects while ignoring others. For Dr. Amar and FAMI, it was all or nothing, a serious marriage of convenience.

Chapter 1: The Story since inception:
Although the recognition of the benefits of both adult stem cells and custom-shaped cannulae became a reality for Dr. Amar and his clinic in the late 1990s, he realized there was still a long path from hypothesis to absolute fact.

To achieve this, he knew he would have to have to overcome two specific challenges. The first was to achieve a comprehensive understanding of the facial anatomy – one that would allow him to navigate every miniscule section of the skull and the myriad overlapping muscle and nerves layered on top of it.

The second challenge would be to confirm a final set of tools to help reach every miniscule section in a way that would guarantee the safe and effective delivery of the adult stem cells, extracted from the same patient. Although Dr. Amar already had a working set of cannulae he had developed using the curvatures of live patients and models as guides, he still felt there was a necessary component was missing as well as consequential sections of the facial anatomy out of reach.

Like so many discoveries in science, overcoming these challenges required an earlier discovery to build upon. In both cases, the aforementioned introduction of naturally preserved models for testing and exploration allowed these final steps to come into view.
By allowing a surgeon, such as Dr. Amar, to explore the facial structure, as it existed in a live patient without the risk of harm to the deep tissue of the face, these natural

models provided a testing ground for how best to reach points long since believed to be beyond the reach of safe procedures. Fig 34:

Working in meticulous detail in the laboratory setting, Dr. Amar entered the new millennium as both an experienced surgeon and fresh-faced researcher, driven by curiosity and the firm knowledge that he was on to something revolutionary.

Following every opportunity for hands-on experience with natural models, Dr. Amar first concentrated on the ability to reach the most pivotal points on the human face as well as reaching as close as humanly possible to the facial vascular system without damage or trauma.

One of the most confounding of these points came with finding a deeper point of entry for the Fossa Temporalis beneath the Zygomatic Arch. Running just above the cheek, between the eye and the ear, the Arch connects the frontal cheek bone and skull's temporal bone, creating a complex challenge to any surgeon, especially one with the intention of entering the fat pads that run beneath it. Fig 34

To reach this cavity located laterally to the eye known as the temporal hollow, a surgeon has to enter the face from underneath the arch, creating a challenge that was impossible to overcome until the introduction of naturally preserved models.

For the first time in his professional life, Dr. Amar had been given the chance to navigate areas in their natural form that had only existed to he and his peers in a theoretical sense. He was able to navigate a final frontier of the facial anatomy, allowing him a confident understanding that would greatly help his surgical skills.

Further, this access allowed Dr. Amar to form the final tools for his set of cannulae. Although he had previously formed his tools to fit the muscular tissue, the use of natural models allowed him to discover the need for longer cannulae in 2002 and a trio meant to be used for the skull the following year.

Or visit:   The Amar Clinic website: Stem cells FAMI rejuvenation