Dr Roger Amar, FAMI Plastic Surgeon, THE BOOK



FAT GRAFTING FAMI (Fat Autograft Muscle Injection)
For more information please call
tlf +34 952 864 698
Amarclinic in the Press

Science of cells in FAMI

Although discussion of the term “Stem Cell” has become commonplace only in the last ten to fifteen years, the theory of naturally regenerative cells dates back over a century.

First coined as a laboratory theory in the middle of the 1900s, stem cells were proposed after researchers recognized that certain types of cells had the capacity to replicate themselves. These cells were tested in myriad forms over the years that followed, though research tended to first focus on animal subjects and then mostly related to their presence in bone marrow.

FAMI research
By the time researchers were able to determine that certain cells did indeed have the ability to replicate in 1989, theoretically without end, stem cells had become an increasingly controversial topic, due mostly to the origin of some stem cells.

Critics pointed to the extraction of embryonic stem cells from foetuses as a cause for ethical concern. Unfortunately, all stem cells tended to be included in such ethical debates, despite the fact that samples can come from a number of different lineages, including those used by Dr. Amar for the completion of the FAMI technique.

While embryonic stem cells are extracted from foetal tissue and cord blood, those cells used by Dr. Amar are derived from so called Ever Young areas. Fig 23.


Vibrabrent stem cells

Those areas continue to create new, vibrant cells regardless of how the aging process may affect the rest of a patient’s body.
According to recent studies, these non-embryonic-stem-cells share many similarities with macrophages, which white blood cells responsible for wound defence and healing. Adipose or fat-derived stem cells (ADSCs) participate in skin-layer wound healing in physiological and pathological conditions due to their ability to promote epithelialization (skin growth) and angiogenesis (vessel growth). Hence, adipose or fat-derived cells represent a new cell source for therapeutic skin-layer wound healing.
Seemingly

composition of adipose tissue

Seemingly unconnected to the aging process, these adult stem cells are best found in fat tissue in the inner thigh and belly of a patient and can be extracted in large quantities. An average sample of a half pound of human fat, removed during a routine liposuction can provide anywhere from 50 to 100 million cells – a number that can double in a 50 hour period thanks to their regenerative power. . Fig 24.

However, an adult stem cell’s point of origin is not the only characteristic that sets it apart from an embryonic sample.
While embryonic stem cells act as essentially blank slates for host cells, adopting the characteristics of the local environment, adult stem cells tend to be more specified in their role. This tends to limit the use of adult stem cells in the production of new tissue, but serves to increase the chance that the newly introduced cells will take to their new host, as it is already shares some characteristics with its host.

In the case of adult stem cells, the fact that they are extracted from the very patient who will ultimately receive them is essential to their ability to replicate cellular tissue. Unlike embryonic stem cells, adult cells are unable to adjust to environments outside their body of origin.

Still, both types of cells act mainly as unspecified building blocks that can renew themselves indefinitely under the right conditions and eventually evolve into more mature cells with specific functions. Theoretically, they act as “master cells” that may be used to replicate and replace any type of cellular tissue. Fig 25


Stem cells difference


Further, these cells have built in restraints that halt growth when their job is done, producing no more and no less new tissue than their host cells demand. This erases the chance that injected cells will produce excess growth or tumours.

While researchers have continued to explore the many possible uses for all stem cells, the availability, reliability and lack of ethical questions have made adult stem cells the more commonly visible of the two.

For Dr. Amar, this acceptance and wide use of adult stem cells represented the next logical step in the evolution of FAMI. Already familiar with the power of regenerative cells, Dr. Amar recognized the role adult stem cells, or pre-adipocytes, could play in providing a natural and precise alternative to traditional fat injections.

Already equipped with a thorough, three-dimensional view of the facial structure, Dr. Amar now had the organic ingredient to produce a natural, lasting result. Familiar with the process and practice of liposuction, Dr. Amar knew that these cells could be easily extracted from a patient and injected to produce the kind of three-dimensional volume he knew was possible.

Still, the question of how he could deliver the safest possible sample, in the safest possible way remained. Traditional methods had relied on clumsy and imprecise scalpels and debris-ridden fat samples, producing dismal and unpredictable results. To ensure the level of quality he knew was possible, Dr. Amar understood that the limitations of modern surgery would have to be pushed – a challenge he would ultimately have to face himself.

Or visit:   The Amar Clinic website: Stem cells FAMI rejuvenation

sombra
 
Société Française de Chirurgie Plastique Sociedad española Cirugía Plástica Member of the American Society for Aesthetic Plastic Surgery
AMAR CLINICC/ Ramón Gómez de la Serna 22, 29600 MarbellaTeléfono: +34 952 864 698E-mail: info@theamarclinic.comSite Map